Intraepithelial carcinoma (Bowen disease) - Carcinoma Mewnepithelaidd (Clefyd Bowen)
☆ Yng nghanlyniadau Stiftung Warentest 2022 o’r Almaen, roedd boddhad defnyddwyr â ModelDerm ond ychydig yn is nag ymgynghoriadau telefeddygaeth taledig.
Achos nodweddiadol ― Carcinoma Mewnepithelaidd (Clefyd Bowen) (Intraepithelial carcinoma (Bowen disease)) gellir ei gamddiagnosio fel ecsema hirbarhaol nad yw'n cosi.
References
Mae Bowen's disease (BD) yn fath o ganser y croen sy'n dechrau yn haen allanol y croen (epidermis) . Mae'n fwy cyffredin mewn Caucasians ac yn aml yn digwydd mewn ardaloedd sy'n agored i olau'r haul, ond gall ymddangos mewn mannau eraill hefyd. Mae BD fel arfer yn ymddangos fel un briw. Mae BD yn aml yn cael ei weld fel arwydd rhybudd cyn i fath mwy difrifol o ganser y croen ddatblygu. I wneud diagnosis o BD, mae meddygon fel arfer yn dibynnu ar archwilio samplau meinwe o dan ficrosgop (biopsi) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Mae Bowen's disease yn effeithio'n bennaf ar unigolion gwyn dros 60 oed. Mae ffactorau risg allweddol yn cynnwys amlygiad hirdymor i'r haul, system imiwnedd wan, amlygiad arsenig, a haint HPV ar y croen. Mae straenau HPV 16, 18, 34, a 48 yn gysylltiedig â chlefyd Bowen mewn ardaloedd gwenerol. Mae cyfranogiad HPV mewn achosion an-genhedlol yn llai clir.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Mae fel arfer yn ymddangos fel ardal erythematous, cennog neu grystiog unrhyw le ar y corff. Y lleoliad mwyaf cyffredin yw coesau isaf.
Gellir ei wella gan wahanol opsiynau triniaeth megis cryotherapi, curettage, rhybuddiad, therapi ffotodynamig, neu dorri'r briw.
○ Diagnosis a Thriniaeth
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy